Workshop on Preclinical Animal Models & Drug Evaluation Techniques

Drug development is the process of bringing a new drug to the market which includes pre-clinical research and clinical research. Throughout history, scientists have been solving medical problems, developing new techniques and treatments, and curing diseases all by using animals models. The pre-clinical research in the drug development process involves use of various animal models for drug screening and evaluation. This together with the toxicity studies involves major portion of the drug development. Pre-clinical animal studies are thus mandatory for any new drug to come into the market. Major medical advancements has been achieved through biomedical research using animal models to study and find a cure for a disease and through animal testing to prove the safety and efficacy of a new treatment. Various animal models are being utilized by the scientists, researchers, academicians and industry personals for drug screening and evaluation. These screening processes involves use of various surgical techniques and instruments. Major challenges in animal experimentation are development and identification of an appropriate animal model, ethical issues in animal handling, methods to standardize and validate animal model and thereby translation of the animal research to human practice.  This workshop intends to address these growing issues as part of plenary lectures in the pre-lunch session. We, at the Institute of Pharmacy, Nirma University have a state of art animal house registered with CPCSEA. Hence, in this workshop practical training would be imparted for surgical models for cardiac hypertrophy, stroke etc. Molecular techniques like polymerase chain reaction (PCR), Enzyme Linked Immunosorbent Assay (ELISA), gel electrophoresis etc. will also be demonstrated. The workshop would also provide hands-on training of instruments like biochemical auto-analyzer, invasive method of measurement of blood pressure, heart rate and hemodynamic parameters etc.